R-Factor-Mediated Resistance to Tetracycline in Proteus mirabilis
نویسندگان
چکیده
منابع مشابه
R-factor-mediated resistance to tetracycline in Proteus mirabilis.
The expression of R-factor-mediated resistance to tetracycline has been compared in Proteus mirabilis and Escherichia coli. Resistance to a range of concentrations of tetracycline was significantly lower in P. mirabilis than in E. coli in both induced and repressed states. Indirect evidence showed that conditions which result in a marked increase in the level of resistance of P. mirabilis harbo...
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The inducible tetracycline resistance determinant isolated from Proteus mirabilis cloned into the plasmid pACYC177 was mutagenized by insertion of a mini-Mu-lac phage in order to define the regions in the cloned sequences encoding the structural and regulatory proteins. Three different types of mutants were obtained: one lost the resistance phenotype and became Lac+; another expressed the resis...
متن کاملTransduction of R factors in Proteus mirabilis and P. rettgeri.
Phage 34 transduces some R factors to Proteus mirabilis strain 13. These transductants can transmit the R factor by conjugation. Transduction frequencies vary from I x I ~-~/plaque-forming unit (p.f.u.) adsorbed (higher than .chromosomal marker transduction) to 5 x Io-8/p.f.u. adsorbed. Transduced drug resistance markers of other R factors were detected only in the presence of resident$factors ...
متن کاملTransduction of R factors by a Proteus mirabilis bacteriophage.
A transducing phage, designated phim, was isolated from a lysogenic strain of Proteus mirabilis and was characterized with respect to its physical and genetic properties. The phage contains double-stranded deoxyribonucleic acid (DNA) with an S(20,w) degrees of 29 which corresponds to a molecular weight of 24 x 10(6) daltons. The base composition of phim DNA was estimated to be 40% guanine plus ...
متن کاملPositive and negative control of R-factor replication in Proteus mirabilis.
Replication of the 50 and 58 moles per cent guanine plus cytosine (%GC) components of R factor 222 in Proteus mirabilis during growth in the presence and absence of chloramphenicol and after shifting exponential- and stationary-phase cells to conditions which inhibit host protein or deoxyribonucleic acid (DNA) synthesis was examined. Chloramphenicol reduced the growth rate but increased the amo...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1973
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.115.1.235-242.1973